Cohesion is the attraction between molecules of the same substance, while adhesion is the attraction between molecules of different substances. Cohesion is the force that helps hold molecules of a single substance together, while adhesion is the force that helps hold molecules from different substances together. Cohesion is responsible for surface tension, which is the ability of a liquid to maintain its shape when acting against gravity. Adhesion is responsible for wetting, which is the ability of a liquid to spread out and cover the surface of a solid.
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